COLD-CE: Cold urticaria and other cold-induced reactions – Comprehensive Evaluation

This international, multi-center, prospective and partly retrospective, observational, cross-sectional academic study aims to improve the understanding of cold urticaria and cold-induced anaphylaxis. Optimal evaluation strategies need to be defined. We hope this project will spread globally and to help improve patient care.

Study type: Questionnaire (physician and patient), stimulation testing

We intend to present the study results at an international congress (preferably EADV or EAACI) and to publish them in peer-reviewed scientific journals. To become a coauthor, you need to include at least 10 patients and contribute to the interpretation of study results and manuscript development. Additional co-authorship criteria are: 15 included patients more = another additional co-authorship, 30 included patients more = another additional co-authorship. The sequence of coauthors who contributed equally to data interpretation and manuscript development will be based on the number of patients included.

Project Lead: Mojca Bizjak, Dorothea Terhorst-Molawi

Project Advisor: Kanokvalai Kulthanan, Marcus Maurer

Steering Committee: Mitja Košnik, Kanokvalai Kulthanan, Marcus Maurer, Raisa Meshkova, Simon Francis Thomsen

Deadline: March 1st 2021 anticipated

Publication 1: Risk factors for systemic reactions in typical cold urticaria: Results from the COLD-CE study

Bizjak, M, Košnik, M, Dinevski, D, et al. Risk factors for systemic reactions in typical cold urticaria: Results from the COLD-CE study. Allergy. 2022; 77: 2185– 2199. doi:10.1111/all.15194December 4, 2021 in Allergy, Volume 77, Issue 7 (July 2022)

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Publication 2: Adrenaline autoinjector is underprescribed in typical cold urticaria patients

Bizjak M, Košnik M, Dinevski D, Thomsen SF, et al. Adrenaline autoinjector is underprescribed in typical cold urticaria patients. Allergy. 2022 Jul;77(7):2224-2229. doi: 10.1111/all.15274. Epub 2022 Mar 14. PMID: 35258111.

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